The crash happened around 3:15 a.m. when the driver of a Toyota Camry lost control and traveled into the median. The vehicle then struck a raised rock cutout, dividing the eastbound and westbound lanes, and then rolled over multiple times, according to police.

After the vehicle came to rest in the middle of the eastbound lanes, it was sideswiped by another vehicle whose driver was unable to see the disabled car in the road, police said.

A female passenger in the Camry sustained life-threatening injuries and was flown to Boston.

The driver and two other passengers sustained serious but non-life-threatening injuries and were taken to Elliot Hospital in Manchester, police said.

The identities of the occupants were being withheld Tuesday, pending notifications to next of kin and further investigation.